Cargando…

Novel broad-spectrum activity-based probes to profile malarial cysteine proteases

Clan CA cysteine proteases, also known as papain-like proteases, play important roles throughout the malaria parasite life cycle and are therefore potential drug targets to treat this disease and prevent its transmission. In order to study the biological function of these proteases and to chemically...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Michele S. Y., Davison, Dara, Sanchez, Mateo I., Anderson, Bethany M., Howell, Stephen, Snijders, Ambrosius, Edgington-Mitchell, Laura E., Deu, Edgar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953825/
https://www.ncbi.nlm.nih.gov/pubmed/31923258
http://dx.doi.org/10.1371/journal.pone.0227341