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Novel broad-spectrum activity-based probes to profile malarial cysteine proteases
Clan CA cysteine proteases, also known as papain-like proteases, play important roles throughout the malaria parasite life cycle and are therefore potential drug targets to treat this disease and prevent its transmission. In order to study the biological function of these proteases and to chemically...
Autores principales: | Tan, Michele S. Y., Davison, Dara, Sanchez, Mateo I., Anderson, Bethany M., Howell, Stephen, Snijders, Ambrosius, Edgington-Mitchell, Laura E., Deu, Edgar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953825/ https://www.ncbi.nlm.nih.gov/pubmed/31923258 http://dx.doi.org/10.1371/journal.pone.0227341 |
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