Novel imaging biomarkers for mapping the impact of mild mitochondrial uncoupling in the outer retina in vivo

PURPOSE: To test the hypothesis that imaging biomarkers are useful for evaluating in vivo rod photoreceptor cell responses to a mitochondrial protonophore. METHODS: Intraperitoneal injections of either the mitochondrial uncoupler 2,4 dinitrophenol (DNP) or saline were given to mice with either highe...

Descripción completa

Detalles Bibliográficos
Autores principales: Berkowitz, Bruce A., Olds, Hailey K., Richards, Collin, Joy, Joydip, Rosales, Tilman, Podolsky, Robert H., Childers, Karen Lins, Hubbard, W. Brad, Sullivan, Patrick G., Gao, Shasha, Li, Yichao, Qian, Haohua, Roberts, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953833/
https://www.ncbi.nlm.nih.gov/pubmed/31923239
http://dx.doi.org/10.1371/journal.pone.0226840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953833/
https://www.ncbi.nlm.nih.gov/pubmed/31923239
http://dx.doi.org/10.1371/journal.pone.0226840

Ejemplares similares