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Nanosheet wrapping-assisted coverslip-free imaging for looking deeper into a tissue at high resolution

In order to achieve deep tissue imaging, a number of optical clearing agents have been developed. However, in a conventional microscopy setup, an objective lens can only be moved until it is in contact with a coverslip, which restricts the maximum focusing depth into a cleared tissue specimen. Until...

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Detalles Bibliográficos
Autores principales: Zhang, Hong, Yarinome, Kenji, Kawakami, Ryosuke, Otomo, Kohei, Nemoto, Tomomi, Okamura, Yosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953877/
https://www.ncbi.nlm.nih.gov/pubmed/31923215
http://dx.doi.org/10.1371/journal.pone.0227650