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Coxiella burnetii Type 4B Secretion System-dependent manipulation of endolysosomal maturation is required for bacterial growth

Upon host cell infection, the obligate intracellular bacterium Coxiella burnetii resides and multiplies within the Coxiella–Containing Vacuole (CCV). The nascent CCV progresses through the endosomal maturation pathway into a phagolysosome, acquiring endosomal and lysosomal markers, as well as acidic...

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Detalles Bibliográficos
Autores principales: Samanta, Dhritiman, Clemente, Tatiana M., Schuler, Baleigh E., Gilk, Stacey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953889/
https://www.ncbi.nlm.nih.gov/pubmed/31869379
http://dx.doi.org/10.1371/journal.ppat.1007855