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RNA Specificity and Autoregulation of DDX17, a Modulator of MicroRNA Biogenesis

DDX17, a DEAD-box ATPase, is a multifunctional helicase important for various RNA functions, including microRNA maturation. Key questions for DDX17 include how it recognizes target RNAs and influences their structures, as well as how its ATPase activity may be regulated. Through crystal structures a...

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Detalles Bibliográficos
Autores principales: Ngo, Tri D., Partin, Alexander C., Nam, Yunsun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953907/
https://www.ncbi.nlm.nih.gov/pubmed/31851931
http://dx.doi.org/10.1016/j.celrep.2019.11.059