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The CDK Pef1 and protein phosphatase 4 oppose each other for regulating cohesin binding to fission yeast chromosomes

Cohesin has essential roles in chromosome structure, segregation and repair. Cohesin binding to chromosomes is catalyzed by the cohesin loader, Mis4 in fission yeast. How cells fine tune cohesin deposition is largely unknown. Here, we provide evidence that Mis4 activity is regulated by phosphorylati...

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Detalles Bibliográficos
Autores principales: Birot, Adrien, Tormos-Pérez, Marta, Vaur, Sabine, Feytout, Amélie, Jaegy, Julien, Alonso Gil, Dácil, Vazquez, Stéphanie, Ekwall, Karl, Javerzat, Jean-Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954021/
https://www.ncbi.nlm.nih.gov/pubmed/31895039
http://dx.doi.org/10.7554/eLife.50556