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The CDK Pef1 and protein phosphatase 4 oppose each other for regulating cohesin binding to fission yeast chromosomes
Cohesin has essential roles in chromosome structure, segregation and repair. Cohesin binding to chromosomes is catalyzed by the cohesin loader, Mis4 in fission yeast. How cells fine tune cohesin deposition is largely unknown. Here, we provide evidence that Mis4 activity is regulated by phosphorylati...
Autores principales: | Birot, Adrien, Tormos-Pérez, Marta, Vaur, Sabine, Feytout, Amélie, Jaegy, Julien, Alonso Gil, Dácil, Vazquez, Stéphanie, Ekwall, Karl, Javerzat, Jean-Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954021/ https://www.ncbi.nlm.nih.gov/pubmed/31895039 http://dx.doi.org/10.7554/eLife.50556 |
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