Widespread activation of developmental gene expression characterized by PRC1-dependent chromatin looping

Polycomb repressive complexes 1 and 2 have been historically described as transcriptional repressors, but recent reports suggest that PRC1 might also support activation, although the underlying mechanisms remain elusive. Here, we show that stage-specific PRC1 binding at a subset of active promoters...

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Detalles Bibliográficos
Autores principales: Loubiere, V., Papadopoulos, G. L., Szabo, Q., Martinez, A-M., Cavalli, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954061/
https://www.ncbi.nlm.nih.gov/pubmed/31950077
http://dx.doi.org/10.1126/sciadv.aax4001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954061/
https://www.ncbi.nlm.nih.gov/pubmed/31950077
http://dx.doi.org/10.1126/sciadv.aax4001

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