Metformin Inhibits Proliferation of Human Thyroid Cancer TPC-1 Cells by Decreasing LRP2 to Suppress the JNK Pathway

OBJECTIVE: To uncover the potential effect of metformin on proliferation and apoptosis of thyroid cancer TPC-1 cell line, and the underlying mechanism. METHODS: Viability, apoptosis and LRP2 level in TPC-1 cells treated with different doses of metformin for different time points were determined. Bes...

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Detalles Bibliográficos
Autores principales: He, Yang, Cao, Lingling, Wang, Li, Liu, Lingping, Huang, Ying, Gong, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954091/
https://www.ncbi.nlm.nih.gov/pubmed/32021253
http://dx.doi.org/10.2147/OTT.S227915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954091/
https://www.ncbi.nlm.nih.gov/pubmed/32021253
http://dx.doi.org/10.2147/OTT.S227915

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