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Metformin Inhibits Proliferation of Human Thyroid Cancer TPC-1 Cells by Decreasing LRP2 to Suppress the JNK Pathway

OBJECTIVE: To uncover the potential effect of metformin on proliferation and apoptosis of thyroid cancer TPC-1 cell line, and the underlying mechanism. METHODS: Viability, apoptosis and LRP2 level in TPC-1 cells treated with different doses of metformin for different time points were determined. Bes...

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Detalles Bibliográficos
Autores principales:	He, Yang, Cao, Lingling, Wang, Li, Liu, Lingping, Huang, Ying, Gong, Xuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954091/ https://www.ncbi.nlm.nih.gov/pubmed/32021253 http://dx.doi.org/10.2147/OTT.S227915

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