Dioscin Inhibited Glycolysis and Induced Cell Apoptosis in Colorectal Cancer via Promoting c-myc Ubiquitination and Subsequent Hexokinase-2 Suppression

PURPOSE: Dioscin is a natural product isolated from traditional Chinese medicines and is reported to have antitumor activities against several cancers. In the present study, we aimed to investigate its potency against colorectal cancers, especially the effects on tumor glycolysis, and to elaborate r...

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Detalles Bibliográficos
Autores principales: Wu, Zhenqian, Han, Xiaodong, Tan, Gewen, Zhu, Qingchao, Chen, Hongqi, Xia, Yang, Gong, Jianfeng, Wang, Zhigang, Wang, Yu, Yan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954095/
https://www.ncbi.nlm.nih.gov/pubmed/32021252
http://dx.doi.org/10.2147/OTT.S224062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954095/
https://www.ncbi.nlm.nih.gov/pubmed/32021252
http://dx.doi.org/10.2147/OTT.S224062

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