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Dioscin Inhibited Glycolysis and Induced Cell Apoptosis in Colorectal Cancer via Promoting c-myc Ubiquitination and Subsequent Hexokinase-2 Suppression
PURPOSE: Dioscin is a natural product isolated from traditional Chinese medicines and is reported to have antitumor activities against several cancers. In the present study, we aimed to investigate its potency against colorectal cancers, especially the effects on tumor glycolysis, and to elaborate r...
Autores principales: | Wu, Zhenqian, Han, Xiaodong, Tan, Gewen, Zhu, Qingchao, Chen, Hongqi, Xia, Yang, Gong, Jianfeng, Wang, Zhigang, Wang, Yu, Yan, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954095/ https://www.ncbi.nlm.nih.gov/pubmed/32021252 http://dx.doi.org/10.2147/OTT.S224062 |
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