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Macropinocytosis drives T cell growth by sustaining the activation of mTORC1

Macropinocytosis is an evolutionarily-conserved, large-scale, fluid-phase form of endocytosis that has been ascribed different functions including antigen presentation in macrophages and dendritic cells, regulation of receptor density in neurons, and regulation of tumor growth under nutrient-limitin...

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Detalles Bibliográficos
Autores principales: Charpentier, John C., Chen, Di, Lapinski, Philip E., Turner, Jackson, Grigorova, Irina, Swanson, Joel A., King, Philip D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954116/
https://www.ncbi.nlm.nih.gov/pubmed/31924779
http://dx.doi.org/10.1038/s41467-019-13997-3