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A scalable method for parameter-free simulation and validation of mechanistic cellular signal transduction network models
The metabolic modelling community has established the gold standard for bottom-up systems biology with reconstruction, validation and simulation of mechanistic genome-scale models. Similar methods have not been established for signal transduction networks, where the representation of complexes and i...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954118/ https://www.ncbi.nlm.nih.gov/pubmed/31934349 http://dx.doi.org/10.1038/s41540-019-0120-5 |