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Hypoxia and transforming growth factor β1 regulation of long non‐coding RNA transcriptomes in human pulmonary fibroblasts

One of the key characteristics of idiopathic pulmonary fibrosis (IPF) is accumulation of excess fibrous tissue in the lung, which leads to hypoxic conditions. Transforming growth factor (TGF) β is a major mediator that promotes the differentiation of fibroblasts to myofibroblasts. However, how hypox...

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Detalles Bibliográficos
Autores principales: Senavirathna, Lakmini K., Huang, Chaoqun, Pushparaj, Samuel, Xu, Dao, Liu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954122/
https://www.ncbi.nlm.nih.gov/pubmed/31925944
http://dx.doi.org/10.14814/phy2.14343