Cargando…
Overexpression of mitochondrial creatine kinase preserves cardiac energetics without ameliorating murine chronic heart failure
Mitochondrial creatine kinase (Mt-CK) is a major determinant of cardiac energetic status and is down-regulated in chronic heart failure, which may contribute to disease progression. We hypothesised that cardiomyocyte-specific overexpression of Mt-CK would mitigate against these changes and thereby p...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954138/ https://www.ncbi.nlm.nih.gov/pubmed/31925563 http://dx.doi.org/10.1007/s00395-020-0777-3 |