Structural basis for adhesion G protein-coupled receptor Gpr126 function

Many drugs target the extracellular regions (ECRs) of cell-surface receptors. The large and alternatively-spliced ECRs of adhesion G protein-coupled receptors (aGPCRs) have key functions in diverse biological processes including neurodevelopment, embryogenesis, and tumorigenesis. However, their stru...

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Detalles Bibliográficos
Autores principales: Leon, Katherine, Cunningham, Rebecca L., Riback, Joshua A., Feldman, Ezra, Li, Jingxian, Sosnick, Tobin R., Zhao, Minglei, Monk, Kelly R., Araç, Demet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954182/
https://www.ncbi.nlm.nih.gov/pubmed/31924782
http://dx.doi.org/10.1038/s41467-019-14040-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954182/
https://www.ncbi.nlm.nih.gov/pubmed/31924782
http://dx.doi.org/10.1038/s41467-019-14040-1

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