Structural basis of liprin-α-promoted LAR-RPTP clustering for modulation of phosphatase activity

Leukocyte common antigen-related receptor protein tyrosine phosphatases (LAR-RPTPs) are cell adhesion molecules involved in mediating neuronal development. The binding of LAR-RPTPs to extracellular ligands induces local clustering of LAR-RPTPs to regulate axon growth and synaptogenesis. LAR-RPTPs in...

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Detalles Bibliográficos
Autores principales: Xie, Xingqiao, Luo, Ling, Liang, Mingfu, Zhang, Wenchao, Zhang, Ting, Yu, Cong, Wei, Zhiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954185/
https://www.ncbi.nlm.nih.gov/pubmed/31924785
http://dx.doi.org/10.1038/s41467-019-13949-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954185/
https://www.ncbi.nlm.nih.gov/pubmed/31924785
http://dx.doi.org/10.1038/s41467-019-13949-x

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