Arf1-mediated lipid metabolism sustains cancer cells and its ablation induces anti-tumor immune responses in mice

Cancer stem cells (CSCs) may be responsible for treatment resistance, tumor metastasis, and disease recurrence. Here we demonstrate that the Arf1-mediated lipid metabolism sustains cells enriched with CSCs and its ablation induces anti-tumor immune responses in mice. Notably, Arf1 ablation in cancer...

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Detalles Bibliográficos
Autores principales: Wang, Guohao, Xu, Junji, Zhao, Jiangsha, Yin, Weiqin, Liu, Dayong, Chen, WanJun, Hou, Steven X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954189/
https://www.ncbi.nlm.nih.gov/pubmed/31924786
http://dx.doi.org/10.1038/s41467-019-14046-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954189/
https://www.ncbi.nlm.nih.gov/pubmed/31924786
http://dx.doi.org/10.1038/s41467-019-14046-9

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