Imprinted Cdkn1c genomic locus cell-autonomously promotes cell survival in cerebral cortex development

The cyclin-dependent kinase inhibitor p57(KIP2) is encoded by the imprinted Cdkn1c locus, exhibits maternal expression, and is essential for cerebral cortex development. How Cdkn1c regulates corticogenesis is however not clear. To this end we employ Mosaic Analysis with Double Markers (MADM) technol...

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Detalles Bibliográficos
Autores principales: Laukoter, Susanne, Beattie, Robert, Pauler, Florian M., Amberg, Nicole, Nakayama, Keiichi I., Hippenmeyer, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954230/
https://www.ncbi.nlm.nih.gov/pubmed/31924768
http://dx.doi.org/10.1038/s41467-019-14077-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954230/
https://www.ncbi.nlm.nih.gov/pubmed/31924768
http://dx.doi.org/10.1038/s41467-019-14077-2

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