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Imprinted Cdkn1c genomic locus cell-autonomously promotes cell survival in cerebral cortex development
The cyclin-dependent kinase inhibitor p57(KIP2) is encoded by the imprinted Cdkn1c locus, exhibits maternal expression, and is essential for cerebral cortex development. How Cdkn1c regulates corticogenesis is however not clear. To this end we employ Mosaic Analysis with Double Markers (MADM) technol...
Autores principales: | Laukoter, Susanne, Beattie, Robert, Pauler, Florian M., Amberg, Nicole, Nakayama, Keiichi I., Hippenmeyer, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954230/ https://www.ncbi.nlm.nih.gov/pubmed/31924768 http://dx.doi.org/10.1038/s41467-019-14077-2 |
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