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Microengineered human blood–brain barrier platform for understanding nanoparticle transport mechanisms

Challenges in drug development of neurological diseases remain mainly ascribed to the blood–brain barrier (BBB). Despite the valuable contribution of animal models to drug discovery, it remains difficult to conduct mechanistic studies on the barrier function and interactions with drugs at molecular...

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Detalles Bibliográficos
Autores principales: Ahn, Song Ih, Sei, Yoshitaka J., Park, Hyun-Ji, Kim, Jinhwan, Ryu, Yujung, Choi, Jeongmoon J., Sung, Hak-Joon, MacDonald, Tobey J., Levey, Allan I., Kim, YongTae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954233/
https://www.ncbi.nlm.nih.gov/pubmed/31924752
http://dx.doi.org/10.1038/s41467-019-13896-7