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Microengineered human blood–brain barrier platform for understanding nanoparticle transport mechanisms
Challenges in drug development of neurological diseases remain mainly ascribed to the blood–brain barrier (BBB). Despite the valuable contribution of animal models to drug discovery, it remains difficult to conduct mechanistic studies on the barrier function and interactions with drugs at molecular...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954233/ https://www.ncbi.nlm.nih.gov/pubmed/31924752 http://dx.doi.org/10.1038/s41467-019-13896-7 |