Genetic aberrations in iPSCs are introduced by a transient G1/S cell cycle checkpoint deficiency

A number of point mutations have been identified in reprogrammed pluripotent stem cells such as iPSCs and ntESCs. The molecular basis for these mutations has remained elusive however, which is a considerable impediment to their potential medical application. Here we report a specific stage at which...

Descripción completa

Detalles Bibliográficos
Autores principales: Araki, Ryoko, Hoki, Yuko, Suga, Tomo, Obara, Chizuka, Sunayama, Misato, Imadome, Kaori, Fujita, Mayumi, Kamimura, Satoshi, Nakamura, Miki, Wakayama, Sayaka, Nagy, Andras, Wakayama, Teruhiko, Abe, Masumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954237/
https://www.ncbi.nlm.nih.gov/pubmed/31924765
http://dx.doi.org/10.1038/s41467-019-13830-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954237/
https://www.ncbi.nlm.nih.gov/pubmed/31924765
http://dx.doi.org/10.1038/s41467-019-13830-x

Ejemplares similares