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Genetic aberrations in iPSCs are introduced by a transient G1/S cell cycle checkpoint deficiency
A number of point mutations have been identified in reprogrammed pluripotent stem cells such as iPSCs and ntESCs. The molecular basis for these mutations has remained elusive however, which is a considerable impediment to their potential medical application. Here we report a specific stage at which...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954237/ https://www.ncbi.nlm.nih.gov/pubmed/31924765 http://dx.doi.org/10.1038/s41467-019-13830-x |