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Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium

Neutrophils are implicated in the pathogenesis of atherosclerosis but are seldom detected in atherosclerotic plaques. We investigated whether neutrophil-derived microvesicles may influence arterial pathophysiology. Here we report that levels of circulating neutrophil microvesicles are enhanced by ex...

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Detalles Bibliográficos
Autores principales: Gomez, Ingrid, Ward, Ben, Souilhol, Celine, Recarti, Chiara, Ariaans, Mark, Johnston, Jessica, Burnett, Amanda, Mahmoud, Marwa, Luong, Le Anh, West, Laura, Long, Merete, Parry, Sion, Woods, Rachel, Hulston, Carl, Benedikter, Birke, Niespolo, Chiara, Bazaz, Rohit, Francis, Sheila, Kiss-Toth, Endre, van Zandvoort, Marc, Schober, Andreas, Hellewell, Paul, Evans, Paul C., Ridger, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954269/
https://www.ncbi.nlm.nih.gov/pubmed/31924781
http://dx.doi.org/10.1038/s41467-019-14043-y