Cargando…
Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium
Neutrophils are implicated in the pathogenesis of atherosclerosis but are seldom detected in atherosclerotic plaques. We investigated whether neutrophil-derived microvesicles may influence arterial pathophysiology. Here we report that levels of circulating neutrophil microvesicles are enhanced by ex...
Autores principales: | Gomez, Ingrid, Ward, Ben, Souilhol, Celine, Recarti, Chiara, Ariaans, Mark, Johnston, Jessica, Burnett, Amanda, Mahmoud, Marwa, Luong, Le Anh, West, Laura, Long, Merete, Parry, Sion, Woods, Rachel, Hulston, Carl, Benedikter, Birke, Niespolo, Chiara, Bazaz, Rohit, Francis, Sheila, Kiss-Toth, Endre, van Zandvoort, Marc, Schober, Andreas, Hellewell, Paul, Evans, Paul C., Ridger, Victoria |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954269/ https://www.ncbi.nlm.nih.gov/pubmed/31924781 http://dx.doi.org/10.1038/s41467-019-14043-y |
Ejemplares similares
-
Homeobox B9 integrates bone morphogenic protein 4 with inflammation at atheroprone sites
por: Souilhol, Celine, et al.
Publicado: (2020) -
Mechanical Activation of Hypoxia-Inducible Factor 1α Drives Endothelial Dysfunction at Atheroprone Sites
por: Feng, Shuang, et al.
Publicado: (2017) -
Atheroprone flow activates inflammation via endothelial ATP-dependent P2X7-p38 signalling
por: Green, Jack P, et al.
Publicado: (2018) -
Angiopoietin-1 enhances neutrophil chemotaxis in vitro and migration in vivo through interaction with CD18 and release of CCL4
por: Burnett, Amanda, et al.
Publicado: (2017) -
Neutrophil-Derived Microvesicle Induced Dysfunction of Brain Microvascular Endothelial Cells In Vitro
por: Ajikumar, Anjana, et al.
Publicado: (2019)