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Up-regulation of P21-activated kinase 1 in osteoarthritis chondrocytes is responsible for osteoarthritic cartilage destruction

Osteoarthritis is mainly caused by a degenerative joint disorder, which is characterized by the gradual degradation of articular cartilage and synovial inflammation. The chondrocyte, the unique resident cell type of articular cartilage, is crucial for the development of osteoarthritis. Previous stud...

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Detalles Bibliográficos
Autores principales: Ma, Wanli, Wang, Xiaohe, Wang, Chunhui, Gong, Mingzhi, Ren, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954364/
https://www.ncbi.nlm.nih.gov/pubmed/31868209
http://dx.doi.org/10.1042/BSR20191017