Conditional deletion of E11/Podoplanin in bone protects against ovariectomy-induced increases in osteoclast formation and activity

E11/Podoplanin (Pdpn) is implicated in early osteocytogenesis and the formation of osteocyte dendrites. This dendritic network is critical for bone modelling/remodelling, through the production of receptor activator of nuclear factor κ B (RANK)-ligand (RANKL). Despite this, the role of Pdpn in the c...

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Detalles Bibliográficos
Autores principales: Staines, Katherine A., Hopkinson, Mark, Dillon, Scott, Stephen, Louise A., Fleming, Robert, Sophocleous, Antonia, Buttle, David J., Pitsillides, Andrew A., Farquharson, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Aging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954370/
https://www.ncbi.nlm.nih.gov/pubmed/31894854
http://dx.doi.org/10.1042/BSR20190329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954370/
https://www.ncbi.nlm.nih.gov/pubmed/31894854
http://dx.doi.org/10.1042/BSR20190329

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