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Conditional deletion of E11/Podoplanin in bone protects against ovariectomy-induced increases in osteoclast formation and activity
E11/Podoplanin (Pdpn) is implicated in early osteocytogenesis and the formation of osteocyte dendrites. This dendritic network is critical for bone modelling/remodelling, through the production of receptor activator of nuclear factor κ B (RANK)-ligand (RANKL). Despite this, the role of Pdpn in the c...
Autores principales: | Staines, Katherine A., Hopkinson, Mark, Dillon, Scott, Stephen, Louise A., Fleming, Robert, Sophocleous, Antonia, Buttle, David J., Pitsillides, Andrew A., Farquharson, Colin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954370/ https://www.ncbi.nlm.nih.gov/pubmed/31894854 http://dx.doi.org/10.1042/BSR20190329 |
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