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Same fold, different properties: polarizable molecular dynamics simulations of telomeric and TERRA G-quadruplexes
DNA and RNA sequences rich in guanine can fold into noncanonical structures called G-quadruplexes (GQs), which exhibit a common stem structure of Hoogsteen hydrogen-bonded guanine tetrads and diverse loop structures. GQ sequence motifs are overrepresented in promoters, origins of replication, telome...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954416/ https://www.ncbi.nlm.nih.gov/pubmed/31807754 http://dx.doi.org/10.1093/nar/gkz1154 |