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Cross-subunit catalysis and a new phenomenon of recessive resurrection in Escherichia coli RNase E

RNase E is a 472-kDa homo-tetrameric essential endoribonuclease involved in RNA processing and turnover in Escherichia coli. In its N-terminal half (NTH) is the catalytic active site, as also a substrate 5′-sensor pocket that renders enzyme activity maximal on 5′-monophosphorylated RNAs. The protein...

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Detalles Bibliográficos
Autores principales: Ali, Nida, Gowrishankar, Jayaraman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954427/
https://www.ncbi.nlm.nih.gov/pubmed/31802130
http://dx.doi.org/10.1093/nar/gkz1152