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A microRNA signature of toxic extrasynaptic N-methyl-D-aspartate (NMDA) receptor signaling

The cellular consequences of N-Methyl-D-Aspartate receptor (NMDAR) stimulation depend on the receptors’ subcellular localization. Synaptic NMDARs promote plasticity and survival whereas extrasynaptic NMDARs mediate excitotoxicity and contribute to cell death in neurodegenerative diseases. The mechan...

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Detalles Bibliográficos
Autores principales: Bas-Orth, Carlos, Koch, Mirja, Lau, David, Buchthal, Bettina, Bading, Hilmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954508/
https://www.ncbi.nlm.nih.gov/pubmed/31924235
http://dx.doi.org/10.1186/s13041-020-0546-0