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A microRNA signature of toxic extrasynaptic N-methyl-D-aspartate (NMDA) receptor signaling
The cellular consequences of N-Methyl-D-Aspartate receptor (NMDAR) stimulation depend on the receptors’ subcellular localization. Synaptic NMDARs promote plasticity and survival whereas extrasynaptic NMDARs mediate excitotoxicity and contribute to cell death in neurodegenerative diseases. The mechan...
Autores principales: | Bas-Orth, Carlos, Koch, Mirja, Lau, David, Buchthal, Bettina, Bading, Hilmar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954508/ https://www.ncbi.nlm.nih.gov/pubmed/31924235 http://dx.doi.org/10.1186/s13041-020-0546-0 |
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