Downregulation of MYPT1 increases tumor resistance in ovarian cancer by targeting the Hippo pathway and increasing the stemness

BACKGROUND: Ovarian cancer is one of the most common and malignant cancers, partly due to its late diagnosis and high recurrence. Chemotherapy resistance has been linked to poor prognosis and is believed to be linked to the cancer stem cell (CSC) pool. Therefore, elucidating the molecular mechanisms...

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Detalles Bibliográficos
Autores principales: Muñoz-Galván, Sandra, Felipe-Abrio, Blanca, Verdugo-Sivianes, Eva M., Perez, Marco, Jiménez-García, Manuel P., Suarez-Martinez, Elisa, Estevez-Garcia, Purificacion, Carnero, Amancio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954568/
https://www.ncbi.nlm.nih.gov/pubmed/31926547
http://dx.doi.org/10.1186/s12943-020-1130-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954568/
https://www.ncbi.nlm.nih.gov/pubmed/31926547
http://dx.doi.org/10.1186/s12943-020-1130-z

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