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KMT2C/D COMPASS complex-associated diseases [K(CD)COM-ADs]: an emerging class of congenital regulopathies

The type 2 lysine methyltransferases KMT2C and KMT2D are large, enzymatically active scaffold proteins that form the core of nuclear regulatory structures known as KMT2C/D COMPASS complexes (complex of proteins associating with Set1). These evolutionarily conserved proteins regulate DNA promoter and...

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Detalles Bibliográficos
Autores principales: Lavery, William J., Barski, Artem, Wiley, Susan, Schorry, Elizabeth K., Lindsley, Andrew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954584/
https://www.ncbi.nlm.nih.gov/pubmed/31924266
http://dx.doi.org/10.1186/s13148-019-0802-2