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Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway

BACKGROUND: Pyroptosis belongs to a novel inflammatory programmed cell death pathway, with the possible prognosis of endometrial cancer related to the terminal protein GSDMD. Hydrogen exerts a biphasic effect on cancer by promoting tumor cell death and protecting normal cells, which might initiate G...

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Detalles Bibliográficos
Autores principales: Yang, Ye, Liu, Ping Yin, Bao, Wei, Chen, Song Jun, Wu, Fang Su, Zhu, Ping Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954594/
https://www.ncbi.nlm.nih.gov/pubmed/31924176
http://dx.doi.org/10.1186/s12885-019-6491-6