Cargando…

Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway

BACKGROUND: Pyroptosis belongs to a novel inflammatory programmed cell death pathway, with the possible prognosis of endometrial cancer related to the terminal protein GSDMD. Hydrogen exerts a biphasic effect on cancer by promoting tumor cell death and protecting normal cells, which might initiate G...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Ye, Liu, Ping Yin, Bao, Wei, Chen, Song Jun, Wu, Fang Su, Zhu, Ping Ya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954594/ https://www.ncbi.nlm.nih.gov/pubmed/31924176 http://dx.doi.org/10.1186/s12885-019-6491-6

Ejemplares similares

Fibroblast growth factor 21 attenuates ventilator-induced lung injury by inhibiting the NLRP3/caspase-1/GSDMD pyroptotic pathway
por: Ding, Peng, et al.
Publicado: (2023)

Blocking Caspase-1/Gsdmd and Caspase-3/-8/Gsdme pyroptotic pathways rescues silicosis in mice
por: Kang, Lulu, et al.
Publicado: (2022)

Tangshen Formula Attenuates Diabetic Kidney Injury by Imparting Anti-pyroptotic Effects via the TXNIP-NLRP3-GSDMD Axis
por: Li, Nan, et al.
Publicado: (2021)

Oxalate‑induced renal pyroptotic injury and crystal formation mediated by NLRP3‑GSDMD signaling in vitro and in vivo
por: Chen, Yue, et al.
Publicado: (2023)

Pyroptotic and non‐pyroptotic effector functions of caspase‐11
por: Abu Khweek, Arwa, et al.
Publicado: (2020)

GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
por: Sborgi, Lorenzo, et al.
Publicado: (2016)

Hydrogen Sulfide Attenuates Neuroinflammation by Inhibiting the NLRP3/Caspase-1/GSDMD Pathway in Retina or Brain Neuron following Rat Ischemia/Reperfusion
por: Yang, Kun-Li, et al.
Publicado: (2022)

ERRα promotes glycolytic metabolism and targets the NLRP3/caspase-1/GSDMD pathway to regulate pyroptosis in endometrial cancer
por: Su, Pingping, et al.
Publicado: (2023)

Simvastatin induces pyroptosis via ROS/caspase-1/GSDMD pathway in colon cancer
por: Xie, Wei, et al.
Publicado: (2023)

Baicalin Alleviates Contrast-Induced Acute Kidney Injury Through ROS/NLRP3/Caspase-1/GSDMD Pathway-Mediated Proptosis in vitro
por: Li, Yanyan, et al.
Publicado: (2022)

GSDMD Mediates LPS-Induced Septic Myocardial Dysfunction by Regulating ROS-dependent NLRP3 Inflammasome Activation
por: Dai, Shanshan, et al.
Publicado: (2021)

Isoorientin Attenuated the Pyroptotic Hepatocyte Damage Induced by Benzo[a]pyrene via ROS/NF-κB/NLRP3/Caspase-1 Signaling Pathway
por: Li, Hao, et al.
Publicado: (2021)

Puerarin Inhibits NLRP3-Caspase-1-GSDMD-Mediated Pyroptosis via P2X7 Receptor in Cardiomyocytes and Macrophages
por: Sun, Shuchan, et al.
Publicado: (2023)

GSDMD-dependent pyroptotic induction by a multivalent CXCR4-targeted nanotoxin blocks colorectal cancer metastases
por: Sala, Rita, et al.
Publicado: (2022)

Baicalein Attenuates Neuroinflammation by Inhibiting NLRP3/Caspase-1/GSDMD Pathway in MPTP-Induced Mice Model of Parkinson’s Disease
por: Rui, Wenjuan, et al.
Publicado: (2020)

Puerarin protects renal ischemia-reperfusion injury in rats through NLRP3/Caspase-1/GSDMD pathway
por: Wang, Kangyu, et al.
Publicado: (2023)

Moxibustion against Cyclophosphamide-Induced Premature Ovarian Failure in Rats through Inhibiting NLRP3-/Caspase-1-/GSDMD-Dependent Pyroptosis
por: Zhang, Cai-rong, et al.
Publicado: (2021)

Activation of adenosine A3 receptor attenuates progression of osteoarthritis through inhibiting the NLRP3/caspase‐1/GSDMD induced signalling
por: Bai, Hui, et al.
Publicado: (2022)

Inhibition of PFKFB Preserves Intestinal Barrier Function in Sepsis by Inhibiting NLRP3/GSDMD
por: Zhang, Yongsheng, et al.
Publicado: (2022)

β-sitosterol alleviates dextran sulfate sodium-induced experimental colitis via inhibition of NLRP3/Caspase-1/GSDMD-mediated pyroptosis
por: Zhang, Di, et al.
Publicado: (2023)

High Glucose Induces the Loss of Retinal Pericytes Partly via NLRP3-Caspase-1-GSDMD-Mediated Pyroptosis
por: Gan, Jinhua, et al.
Publicado: (2020)

An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages
por: de Vasconcelos, Nathalia Moraes, et al.
Publicado: (2020)

NLRP3/caspase-1/GSDMD–mediated pyroptosis exerts a crucial role in astrocyte pathological injury in mouse model of depression
por: Li, Shanshan, et al.
Publicado: (2021)

Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer
por: Teng, Jin-Feng, et al.
Publicado: (2020)

HDAC11 promotes both NLRP3/caspase-1/GSDMD and caspase-3/GSDME pathways causing pyroptosis via ERG in vascular endothelial cells
por: Yao, Feng, et al.
Publicado: (2022)

Cold Stress Induced Liver Injury of Mice through Activated NLRP3/Caspase-1/GSDMD Pyroptosis Signaling Pathway
por: Liu, Yuanyuan, et al.
Publicado: (2022)

Hemoglobin Derived from Subarachnoid Hemorrhage-Induced Pyroptosis of Neural Stem Cells via ROS/NLRP3/GSDMD Pathway
por: Yue, Tingting, et al.
Publicado: (2023)

Podoplanin neutralization reduces thrombo-inflammation in experimental ischemic stroke by inhibiting interferon/caspase-1/GSDMD in microglia
por: Qian, Shuang, et al.
Publicado: (2022)

Downregulated XBP-1 Rescues Cerebral Ischemia/Reperfusion Injury-Induced Pyroptosis via the NLRP3/Caspase-1/GSDMD Axis
por: Zhang, Yueting, et al.
Publicado: (2022)

Cisplatin Induces Pyroptosis via Activation of MEG3/NLRP3/caspase-1/GSDMD Pathway in Triple-Negative Breast Cancer
por: Yan, Honglin, et al.
Publicado: (2021)

Mitochondrial ROS promote macrophage pyroptosis by inducing GSDMD oxidation
por: Wang, Yufang, et al.
Publicado: (2019)

Emodin Alleviates High-Glucose-Induced Pancreatic β-Cell Pyroptosis by Inhibiting NLRP3/GSDMD Signaling
por: Xing, Yiqian, et al.
Publicado: (2022)

Empagliflozin protects diabetic pancreatic tissue from damage by inhibiting the activation of the NLRP3/caspase-1/GSDMD pathway in pancreatic β cells: in vitro and in vivo studies
por: Liu, Pan, et al.
Publicado: (2021)

Suppression of NLRP3/Caspase-1/GSDMD Mediated Corneal Epithelium Pyroptosis Using Melatonin-Loaded Liposomes to Inhibit Benzalkonium Chloride-Induced Dry Eye Disease
por: Lou, Qi, et al.
Publicado: (2023)

Scorpion Venom Antimicrobial Peptides Induce Caspase-1 Dependant Pyroptotic Cell Death
por: Elrayess, Ranwa A., et al.
Publicado: (2022)

Berberine Reduces Renal Cell Pyroptosis in Golden Hamsters with Diabetic Nephropathy through the Nrf2-NLRP3-Caspase-1-GSDMD Pathway
por: Ding, Baozhu, et al.
Publicado: (2021)

BIRC5 Inhibition Is Associated with Pyroptotic Cell Death via Caspase3-GSDME Pathway in Lung Adenocarcinoma Cells
por: Zhang, Qingwei, et al.
Publicado: (2023)

Calcitriol Alleviates Hyperosmotic Stress-Induced Corneal Epithelial Cell Damage via Inhibiting the NLRP3–ASC–Caspase-1–GSDMD Pyroptosis Pathway in Dry Eye Disease
por: Zhang, Jing, et al.
Publicado: (2021)

Oxidized Low Density Lipoprotein Induced Caspase-1 Mediated Pyroptotic Cell Death in Macrophages: Implication in Lesion Instability?
por: Lin, Jing, et al.
Publicado: (2013)

Gasdermin D in peripheral nerves: the pyroptotic microenvironment inhibits nerve regeneration
por: Tao, Ye, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_hepfv3bptahbqis2vibt8f8ait