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LncRNA MEG3 promotes melanoma growth, metastasis and formation through modulating miR-21/E-cadherin axis

BACKGROUND: Melanoma is the most aggressive type of skin cancer with high mortality rate and poor prognosis. lncRNA MEG3, a tumor suppressor, is closely related to the development of various cancers. However, the role of lncRNA MEG3 in melanoma has seldom been studied. METHODS: RT-PCR was used to ex...

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Detalles Bibliográficos
Autores principales: Wu, Liangcai, Zhu, Lifei, Li, Yanchang, Zheng, Zhixin, Lin, Xi, Yang, Chaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954595/
https://www.ncbi.nlm.nih.gov/pubmed/31938020
http://dx.doi.org/10.1186/s12935-019-1087-4