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DECENT: differential expression with capture efficiency adjustmeNT for single-cell RNA-seq data
MOTIVATION: Dropout is a common phenomenon in single-cell RNA-seq (scRNA-seq) data, and when left unaddressed it affects the validity of the statistical analyses. Despite this, few current methods for differential expression (DE) analysis of scRNA-seq data explicitly model the process that gives ris...
Autores principales: | Ye, Chengzhong, Speed, Terence P, Salim, Agus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954660/ https://www.ncbi.nlm.nih.gov/pubmed/31197307 http://dx.doi.org/10.1093/bioinformatics/btz453 |
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