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Type I fatty acid synthase trapped in the octanoyl‐bound state

De novo fatty acid biosynthesis in humans is accomplished by a multidomain protein, the Type I fatty acid synthase (FAS). Although ubiquitously expressed in all tissues, fatty acid synthesis is not essential in normal healthy cells due to sufficient supply with fatty acids by the diet. However, FAS...

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Detalles Bibliográficos
Autores principales: Rittner, Alexander, Paithankar, Karthik S., Himmler, Aaron, Grininger, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954729/
https://www.ncbi.nlm.nih.gov/pubmed/31811668
http://dx.doi.org/10.1002/pro.3797