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Engineering of Naproxen Loaded Polymer Hybrid Enteric Microspheres for Modified Release Tablets: Development, Characterization, in silico Modelling and in vivo Evaluation

BACKGROUND: Naproxen (NP) is a non-steroidal anti-inflammatory drug with poor aqueous solubility and low oral bioavailability, which may lead to therapeutic failure. NP causes crucial GIT irritation, bleeding, and peptic and duodenal ulcers. PURPOSE OF THE STUDY: This study aimed to engineer and cha...

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Detalles Bibliográficos
Autores principales: Hameed, Hajra Afeera, Khan, Shahzeb, Shahid, Muhammad, Ullah, Riaz, Bari, Ahmed, Ali, Syed Saeed, Hussain, Zahid, Sohail, Muhammad, Khan, Shafi Ullah, Htar, Thet Thet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954845/
https://www.ncbi.nlm.nih.gov/pubmed/32021089
http://dx.doi.org/10.2147/DDDT.S232111