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Clinical and MRI efficacy of sc IFN β-1a tiw in patients with relapsing MS appearing to transition to secondary progressive MS: post hoc analyses of PRISMS and SPECTRIMS

This study evaluated efficacy of subcutaneous (sc) interferon beta-1a (IFN β-1a) 44 µg 3 × weekly (tiw) in patients appearing to transition from relapsing–remitting multiple sclerosis (RRMS) to secondary progressive MS (SPMS). The PRISMS study included 560 patients with RRMS (EDSS 0–5.0; ≥ 2 relapse...

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Detalles Bibliográficos
Autores principales: Freedman, Mark S., Brod, Staley, Singer, Barry A., Cohen, Bruce A., Hayward, Brooke, Dangond, Fernando, Coyle, Patricia K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954891/
https://www.ncbi.nlm.nih.gov/pubmed/31559532
http://dx.doi.org/10.1007/s00415-019-09532-5