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Comparative Pharmacokinetic Study of Taxifolin after Oral Administration of Fructus Polygoni Orientalis Extract in Normal and Fibrotic Rats by UPLC-MS/MS

Fructus polygoni orientalis (FPO) is widely used in clinical practice in China, especially in treatment of liver diseases including viral hepatitis, liver fibrosis, and liver cirrhosis. However, its pharmacokinetic (PK) alterations in liver fibrotic rats have rarely been reported. To study whether t...

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Detalles Bibliográficos
Autores principales: Wei, Feili, Guo, Li, Xu, Yongsong, Chen, Dexi, Gong, Muxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955125/
https://www.ncbi.nlm.nih.gov/pubmed/31976002
http://dx.doi.org/10.1155/2019/9348075