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BNC1 regulates cell heterogeneity in human pluripotent stem cell-derived epicardium

The murine developing epicardium heterogeneously expresses the transcription factors TCF21 and WT1. Here, we show that this cell heterogeneity is conserved in human epicardium, regulated by BNC1 and associated with cell fate and function. Single cell RNA sequencing of epicardium derived from human p...

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Detalles Bibliográficos
Autores principales: Gambardella, Laure, McManus, Sophie A., Moignard, Victoria, Sebukhan, Derya, Delaune, Agathe, Andrews, Simon, Bernard, William G., Morrison, Maura A., Riley, Paul R., Göttgens, Berthold, Gambardella Le Novère, Nicolas, Sinha, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955213/
https://www.ncbi.nlm.nih.gov/pubmed/31767620
http://dx.doi.org/10.1242/dev.174441