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Establishment of a novel culture method for maintaining intestinal stem cells derived from human induced pluripotent stem cells

The small intestine plays an important role in the pharmacokinetics of orally administered drugs due to the presence of drug transporters and drug-metabolizing enzymes. However, few appropriate methods exist to investigate intestinal pharmacokinetics. Induced pluripotent stem (iPS) cells can form va...

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Detalles Bibliográficos
Autores principales: Kondo, Satoshi, Mizuno, Shota, Hashita, Tadahiro, Iwao, Takahiro, Matsunaga, Tamihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955217/
https://www.ncbi.nlm.nih.gov/pubmed/31919043
http://dx.doi.org/10.1242/bio.049064