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The adaptor proteins HAP1a and GRIP1 collaborate to activate the kinesin-1 isoform KIF5C
Binding of motor proteins to cellular cargoes is regulated by adaptor proteins. HAP1 and GRIP1 are kinesin-1 adaptors that have been implicated individually in the transport of vesicular cargoes in the dendrites of neurons. We find that HAP1a and GRIP1 form a protein complex in the brain, and co-ope...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955223/ https://www.ncbi.nlm.nih.gov/pubmed/31757889 http://dx.doi.org/10.1242/jcs.215822 |