CRISPR-mediated modeling and functional validation of candidate tumor suppressor genes in small cell lung cancer

Small cell lung cancer (SCLC) is a highly aggressive subtype of lung cancer that remains among the most lethal of solid tumor malignancies. Recent genomic sequencing studies have identified many recurrently mutated genes in human SCLC tumors. However, the functional roles of most of these genes rema...

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Detalles Bibliográficos
Autores principales: Ng, Sheng Rong, Rideout, William M., Akama-Garren, Elliot H., Bhutkar, Arjun, Mercer, Kim L., Schenkel, Jason M., Bronson, Roderick T., Jacks, Tyler
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955235/
https://www.ncbi.nlm.nih.gov/pubmed/31871154
http://dx.doi.org/10.1073/pnas.1821893117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955235/
https://www.ncbi.nlm.nih.gov/pubmed/31871154
http://dx.doi.org/10.1073/pnas.1821893117

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