Cargando…

Circulating gluten‐specific, but not CMV‐specific, CD39(+) regulatory T cells have an oligoclonal TCR repertoire

OBJECTIVES: Understanding the T cell receptor (TCR) repertoire of regulatory CD4(+) T‐cell (Treg) populations is important for strategies aiming to re‐establish tolerance in autoimmune diseases. We studied circulating deamidated gluten‐epitope‐specific CD39(+) Tregs in patients with coeliac disease...

Descripción completa

Detalles Bibliográficos
Autores principales: Cook, Laura, Munier, C Mee Ling, Seddiki, Nabila, Hardy, Melinda Y, Anderson, Robert P, Zaunders, John, Tye‐Din, Jason A, Kelleher, Anthony D, van Bockel, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955237/
https://www.ncbi.nlm.nih.gov/pubmed/31956412
http://dx.doi.org/10.1002/cti2.1096